Michelangelo Merisi da Caravaggio1603
Sacrifice of Isaac
The knife is raised; the angel seizes Abraham's wrist and points to the ram caught in the thicket. Uffizi, Florence.

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Michelangelo Merisi da Caravaggio was a Lombard painter active in Rome, Naples, Malta, and Sicily whose radical chiaroscuro and street-modeled saints reshaped European religious painting. Between the Contarelli Matthew cycle (1599–1602) and his final canvases sent from Naples in 1610, he produced roughly thirty canonical biblical works.
