St. Ambrose Cathedral

About this church

St. Ambrose Cathedral is a Roman Catholic cathedral at 607 High Street in downtown Des Moines, Iowa. Weekend Masses are held Saturday at 4:00 p.m. and Sunday at 8:30 a.m. and 11:00 a.m., with a rosary before the Sunday morning Mass. Weekday Masses are at 12:10 p.m. Monday through Friday, preceded by a rosary at 11:45 a.m., and there is a Saturday morning Mass at 8:00 a.m. Reconciliation is offered Wednesdays from 10:30 to 11:30 a.m. and Saturdays from 2:30 to 3:30 p.m., Adoration is Fridays from 10:00 to 11:30 a.m., and Holy Hour is Mondays from 5:00 to 6:00 p.m. Masses are livestreamed on the cathedral's YouTube page.

Visitors can park behind the cathedral at any time, west of the cathedral on weekends and evenings, or on the street, which is free on Sundays. The parish office is open weekdays from 9:00 a.m. to 4:00 p.m. Ministries and activities include a youth ministry with fundraising and trips to Catholic youth events, a children's choir for grades three through five, a young adult Bible study on Sunday afternoons in the Parish Hall, a St. Vincent de Paul chapter with food pantries, liturgical ministries such as ushers, lectors, cantors, and altar servers, and support for the Connection Cafe lunch program. Confirm times with the parish.

Researched from the church’s official website and reviewed October 5, 2026. Sources: Homepage: Mass, confession, adoration times · Worship: schedule and livestream · Visitors: parking and accessibility · Parish activities and outreach

Service times

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Hours

Published hours can change. Confirm them directly with the church before visiting.

Location